SPLICE is a sexy, fantasy sci-fi thriller directed by Vincenzo Natali who brought us 1997's cult sci-fi classic, CUBE. Clive (ADRIEN BRODY) and Elsa (SARAH POLLEY) are scientist superstars, famous for splicing DNA from different animals to create bizarre hybrids. They are as in love with each other as they are with their work. And they want to go the next step: splice animal and human DNA. But when their corporate financiers refuse, they decide to experiment in secret. The result is Dren: an amazing creature whose rapid life cycle takes her from baby to adult in a matter of months. As Clive and Elsa struggle to keep Dren a secret, their connection to their creation evolves from scientific to personal. Ultimately, Dren exceeds the couple's wildest dreams – and their most terrifying nightmares.